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小兒에서 Guillain-Barre´ 症候群에 對한 臨床的觀察

Clinical Studies on Guillain-Barre´ Syndrome in Children

소아과 1969년 12권 1호 p.13 ~ 20
김지백,
소속 상세정보
김지백 (  ) - 연세대학교 의과대학 소아과학교실

Abstract


Recently there has been a trend to increase the number of the diahnosed cases which called for the special attention of the pediatrician.
Author present here with the thirty six cases observed in pediatric age group.
The records of all patients which were extensively studied and diagnosed as Guillain-Barre' syndrome were reviewed both at Severance hospital and Wonju Union Christian Hospital for the period of five years from Jan. 1959 to Dec. 1963.
1) Twenty seven cases were found in males and 9 cases were female, in a ratio of three to one. The age ranged from one and a half years to 15 years with the peak incidence in the preschool age group.
2) Twenty nine cases of the 36 had preceding infections, 18 of which were upper respiratory in nature.
3) On admission, most of them complained of muscle weakness or paralysis and a few had meningeal signs, all patients were afebrile.
4) Physical findings revealed paralysis of lower extremities in all 36, upper extremities in 16, cranial nerve in 9, and respiratory muscles in 5 cases. In all but two cases deep tendon reflex was either diminished or absent.
5) Albumino-cytologic dissociation of cerebrospinal fluids were detected in 28 cases and the remaining 8 cases were found to have no increase in protein level.
6) Twenty seven cases of the 36 were improved within 6 months and 2 were dead.
Fatality rate diminished since the commencement of steroid therapy combined with physiotherapy, and prognosis in children was better than that of aged group.

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