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Chloramphenicol 藥劑投與後 小兒 血液內含量 및 尿中 排尿量에 對하여

Plasma Level and Urinary Excretion Dose of Chloramphenicol

소아과 1969년 12권 12호 p.27 ~ 29
박민화,
소속 상세정보
박민화 (  ) - 전남대학교 의과대학 소아과학교실

Abstract


Blood plasma concentration of Chloramphenicol was studied with single intramuscular injection of fChloramphenicol 100 mg/kg in dose to 5 cases of Typhoid fever and 5 cases of Purulent meningitis. Followings were the results.
Blood level reached to maximal concentration one to two hours after the administration, maintained :axe level until four to five hours, and then showed progressive decrease.
After 24 hours it disappeared completely from the plasma. It was shown from the above data that intramuscular injection of Chloramphenicol should be repeated with interval of four to six hours for .maintenance of effective therapeutic blood concentration.

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KoreaMed
KAMS