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中樞神經系 疾患에 있어서의 腦脊髓液內 GOT, GPT 活性度와 豫後와의 關係에 關한 檢討

The Correlation between the Prognosis and the GOT and GPT Activities in Cerebrospinal Fluid (C.S.F.) in Central Nervous System (CNS) Disease

소아과 1970년 13권 12호 p.1 ~ 7
홍영식,
소속 상세정보
홍영식 (  ) - 서울대학교 의과대학 소아과학교실

Abstract


The glutamic oxaloacetic transaminase(GOT), glutamic pyruvic transaminase(GPT) activities, protein and sugar values in cerebrospinal fluid(CSF) were examined in central nervous system diseases and compared with control group and summary of the results are as followings.
1) The GOT and GPT activities in control group are 12.4±4.6 units and 10.5±5.7 units.
2) The GPT activity in CSF in each CNS disease group is similar to that of the control group without any association of the severity of the CNS diseases. It is acertained that the values of protein and sugar os observed to be corresponded to each disease.
3) The GOT activity in CNS disease except the tuberculous meningitis is significantly elevated compared to those of other CNS diseases group.
4) The association between the prognosis and GOT activity in the tuberculous meningitis is not clear but in other disease group it seems that the prognosis is most often worse in cases with higher GOT activity.

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