잠시만 기다려 주세요. 로딩중입니다.

Growth Pattern of the Neo-Aorta after Arterial Switch Operation during Childhood

Korean Circulation Journal 2021년 51권 1호 p.83 ~ 93
차설기, 백재숙, 유정진, 김영휘, 권보상, 최은석, 박천수, 윤태진,
소속 상세정보
차설기 ( Cha Seul-Gi ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiology
백재숙 ( Baek Jae-Suk ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiology
유정진 ( Yu Jeong-Jin ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiology
김영휘 ( Kim Young-Hwue ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiology
권보상 ( Kwon Bo-Sang ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiac Surgery
최은석 ( Choi Eun-Seok ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiac Surgery
박천수 ( Park Chun-Soo ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiac Surgery
윤태진 ( Yun Tae-Jin ) - University of Ulsan College of Medicine Asan Medical Center Division of Pediatric Cardiac Surgery

Abstract


Background and Objectives: Neo-aortic root dilatation (ARD) and annular dilatation (AAD) tend to develop after arterial switch operation (ASO). However, the trend of neo-aortic growth has not been well established. This paper aims to identify this trend, its associated factors, and predictors of neo-aortic dilatation after ASO.

Methods: We analyzed the growth trend of the neo-aortic root, annulus, and sinotubular junction (STJ) z-scores using random coefficients model and the risk factors affecting neo-aortic dilatation in 163 patients who underwent ASO from 2006 to 2015.

Results: Among 163 patients, 41 had a ventricular septal defect, and 11 had Taussig-Bing (TB) anomaly. The median follow-up duration was 6.61 years. The increased in the neo-aortic root z-score was different between the trapdoor and non-trapdoor coronary artery transfer techniques (0.149/year, p<0.001 vs. 0.311/year, p<0.001). Moreover, the neo-aortic annulus and STJ z-score significantly increased over time after ASO (0.067/year, p<0.001; 0.309/year, p<0.001). Pulmonary artery banding (PAB) was rather a negative affecting factor. The probabilities of freedom from ARD, AAD, and neo-aortic STJ dilatation at 10 years after ASO were 33.4%, 53.9%, and 65.4%. Neo- aortic regurgitation within 1 year was the predictor of ARD, AAD, and neo-aortic STJ dilatation. TB anomaly, PAB, and native pulmonary sinus z-score were other predictors for ARD.

Conclusion: The growth of neo-aortic root, annulus, and STJ after ASO was greater than somatic growth during childhood. The coronary artery transfer technique affected the growth pattern of the neo-aortic root.

키워드

Aorta; Dilatation; Arterial switch operation

원문 및 링크아웃 정보

 

등재저널 정보