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Differences in Symptoms, Functions, and Their Outcomes According to the Degree of Trauma in Patients with Early Psychosis

신경정신의학 2020년 59권 3호 p.228 ~ 235
문서영, 윤지애, 이규영, 박염홍, 김성완, 이봉주, 이승환, 김정진, 원승희, 김승현, 강시현, 김의태, 정영철, 유제춘,
소속 상세정보
문서영 ( Moon Seo-Young ) - Eulji University Hospital Department of Neuropsychiatry
윤지애 ( Yoon Ji-Ae ) - Eulji University Hospital Department of Neuropsychiatry
이규영 ( Lee Kyu-Young ) - Eulji University School of Medicine Department of Neuropsychiatry
박염홍 ( Piao Yan-Hong ) - Chonbuk National University Medical School Department of Psychiatry
김성완 ( Kim Sung-Wan ) - Chonnam National University Medical School Department of Psychiatry
이봉주 ( Lee Bong-Ju ) - Inje University College of Medicine Department of Psychiatry
이승환 ( Lee Seung-Hwan ) - Inje University College of Medicine Department of Psychiatry
김정진 ( Kim Jung-Jin ) - Catholic University College of Medicine Department of Psychiatry
원승희 ( Won Seung-Hee ) - Kyungpook National University School of Medicine Department of Psychiatry
김승현 ( Kim Seung-Hyun ) - Korea University College of Medicine Department of Psychiatry
강시현 ( Kang Shi-Hyun ) - Seoul National Hospital Department of Psychiatry
김의태 ( Kim Eui-Tae ) - Seoul National University Bundang Hospital Department of Psychiatry
정영철 ( Chung Young-Chul ) - Chonbuk National University Medical School Department of Psychiatry
유제춘 ( Yu Je-Chun ) - Eulji University Hospital Department of Neuropsychiatry

Abstract


Objectives: There has been growing interest in the relationship between mental illness and premorbid trauma recently. The purpose of this study was to examine the difference in symptoms, functions, and their outcomes according to the degree of trauma in patients with early psychosis.

Methods: The study involved 226 people who participated in the Korean Early Psychosis Cohort Study, and we divided the participants into two groups according to the degree of trauma. Positive and Negative Syndrome Scale (PANSS) and Social and Occupational Functioning Assessment Scale (SOFAS) were compared at the start of the study and at 12 months after the treatment using paired t-test and repeated measures analysis of variance.

Results: At the beginning of the study, there was no significant difference between the two groups. But after 12 months of treatment, the high trauma group showed less improvement in PANSS negative score, general psychopathological score, total score, and SOFAS than the low trauma group.

Conclusion: In patients with early psychosis and at least moderate severity of premorbid trauma, negative symptoms, general psychopathological, and social and occupational functional improvements after treatment are less.

키워드

정신증; 외상; 정신병적 증상; 사회직업기능
Trauma; Psychosis; Psychotic symptoms; Social and occupational functioning

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