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5-Chloro-8-Quinolinol 誘導體의 抗아메바 症劑로서의 動物試驗

Animal Tests of New 5-Chloro-8-quinolinol Derivatives as Amebicides

약학회지 1960년 5권 1호 p.56 ~ 57
조윤성,
소속 상세정보
조윤성 (  ) - Seoul National University College of Pharmacy

Abstract


Three new 5-chloro-8-quinolinol derivatives such as
5-chloro-7-[4-(2-N-pyrrolidylethyl)-1-piperidylmethyl]-8-quinolinol
5-chtoro-7-[4-(2-N-piperidylethyl)-1-piperidylmethyl]-8-quinolinol
and 5-chloro-7-[2-N-morpholinylethyl)-1-piperidylmethyl]-8-quinolinol
were synthesized and found to be effective against Entamoeba histolytica in vitro and against experimental intestinal amebiasis in rats.
(Received November 11. 1959)

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