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Lycoctonum 屬植物成分의 藥理學的 硏究 Ⅰ

Pharmacological Study of Components from Lycoctonum Sp. Ⅰ

약학회지 1963년 7권 4호 p.86 ~ 91
김재완,
소속 상세정보
김재완 (  ) - Chungbuk National University Deptarment of Pharmacy

Abstract


Crystal A and B were isolated from L. pseudo-laeve Nakai and their pkarmacological action was observed. Crystal A, in dose of 5×10^(-4)∼5×10^(-5) g/㎖, stimulated excised frog heat but at 2.5×10^(-6) ~0.5×10^(-5) g/㎖ of cystal B, depressant effect was observed. Mild stimulation of rhythmicity of exeised rabbit intestine was produced by 1×10^(-4) g/㎖ of crystal A and 2×10^(-4) g/㎖ of crystal B. Harked depression of tone was produced by 2×10^(-4) g/㎖ of crystal A, antagonizing by pilocarpine. Crystal B(4×10^(-4) gm/ℓ) produced mild stimulation, followed by depression of tone. No curare-like action on excised frog abdominal muscle was elicited with both susbtances.

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