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COVID-19 백신 접종 후 월경 이상 사례 관련 온라인 건강상담 내용의 분석: 약물 감시에서 소셜미디어 자료의 활용가능성 Analysis of Online Health Counseling on Abnormal Menstruation after COVID-19 Vaccination: The Potential of Utilizing Social Media Data for Pharmacovigilance

약학회지 2023년 67권 5호 p.294 ~ 301
이재륜, 전수민, 김혜원, 안정연, 정솔미, 권진원,
소속 상세정보
이재륜 ( Lee Jae-Ryoun ) 

전수민 ( Jeon Soo-Min ) 

김혜원 ( Kim Hye-Won ) 

안정연 ( An Jeong-Yeon ) 

정솔미 ( Jeong Sol-Mi ) 

권진원 ( Kwon Jin-Won ) 

Abstract


Recent developments in big data technologies have highlighted the potential of enhancing the role ofpharmacovigilance. This study aims to assess the potential of utilizing social media for pharmacovigilance using onlinehealth counseling on abnormal menstruation after receiving vaccination for coronavirus disease. We crawled relevant postsregarding vaccine adverse events published on Naver Jisik-iN from February 2021 to August 2022 using keywords“vaccine” and “menstruation.” After preprocessing all collected posts, selected posts were classified based on vaccinationinformation and type of adverse events. A descriptive statistical analysis was performed to analyze the characteristics andtiming of the selected posts and their association with vaccination. Following preprocessing, 4,154 posts were chosen, andthe highest number of posts was generated in October 2021. Among them, 87.75% (n=3,645) were posted after vaccination. Of the 3,645 posts, certain, probable, and possible associations were identified in 63.40, 4.83, and 31.74% posts. The most frequently reported symptom was change in the menstrual cycle, and serious adverse events that required medical attention were observed in 3.05% cases. The study results present a potential pharmacovigilance strategy that leverages social media to complement the voluntary reporting system.

키워드

Pharmacovigilance; Social media; Covid-19 vaccine; Adverse events; Abnormal menstruation

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