出血性 Shock에서 Glucagon이 胸管淋巴量에 미치는 影響에 關하여
Effect of Glucagon on Thoracic Duct Lymph Flow in Hemorrhagic Shock
張秀一, 洪善熹,
소속 상세정보
張秀一 ( )
慶北醫大 外科學敎室
洪善熹 ( )
慶熙醫大 外科學敎室
KMID : 0371319740160080001
Abstract
Glucagon, the hyperglycemic glycogenolytic hormone, has been shown to increase total hepatic blood flow in man and in the dog by several investigators. However, the effect of glucagon on the other vascular beds has been subject to much less study and a few author reported that the adminstration of glucagon produced a significant inotropic and chronotropic action on the heart and slight decrease of systemic vascular resistance. The effect of glucagon on the thoracic duct lymph* flow has not been investigated.
This experimental study was carried out to observe the effect of glucagon on the thoracic duct lymph flow in hemorrhagic shock.
Following the intravenous adminstration of glucagon in six spienectomized mongrel dogs with hemorrhagic shock of 63-60 mmHg blood pressure, femoral artery pressure showed no change, central venous pressure was slightly increased and the lymph flow of thoracic duct was considerably increased. No relation between blood glucose level and increment of thoracic duct lymph flow was noted.
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