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Short- and mid-term outcomes of transanal versus laparoscopic total mesorectal excision for low rectal cancer: a meta-analysis

Annals of Surgical Treatment and Research 2021년 100권 2호 p.86 ~ 99
Ren Jingqing, Luo Huixing, Liu Shaojie, Wang Bailin, Wu Fan,
소속 상세정보
 ( Ren Jingqing ) - Jinan University Medical College Guangzhou Red Cross Hospital Department of General Surgery
 ( Luo Huixing ) - Jinan University Medical College Guangzhou Red Cross Hospital Department of General Surgery
 ( Liu Shaojie ) - Jinan University Medical College Guangzhou Red Cross Hospital Department of General Surgery
 ( Wang Bailin ) - Jinan University Medical College Guangzhou Red Cross Hospital Department of General Surgery
 ( Wu Fan ) - Jinan University Medical College Guangzhou Red Cross Hospital Department of General Surgery

Abstract


Purpose: The current meta-analysis combining mid and low rectal cancer with no meta-analysis only for low rectal cancer was seen. This meta-analysis was to compare the short- and mid-term outcomes of the transanal total mesorectal excision (TaTME) vs. laparoscopic total mesorectal excision (LaTME) for low rectal cancer.

Methods: A systematic literature search was conducted using the web-based databases; China National Knowledge Infrastructure, Chinese BioMedical Database, PubMed, Embase, Cochrane Central Register of Controlled Trials, and Wanfang Database. Randomized controlled trials (RCTs) were evaluated using the Jadad scale and non-RCTs (NRCs) were evaluated using the Newcastle-Ottawa Scale.

Results: Ten studies (2 RCTs and 8 NRCs) involving 772 patients were included. Among them, 378 patients underwent TaTME and 394 patients underwent LaTME. Compared with the LaTME group, the conversion rate was low (risk ratio [RR], 0.25; 95% confidence interval [CI], 0.11?0.54; P < 0.001), the circumferential resection margin (CRM) involvement was low (RR, 0.48; 95% CI, 0.27?0.86; P = 0.010), and the hospital stay was short (mean difference, ?1.72; 95% CI, ?2.89 to ?0.55; P = 0.004) in the TaTME group. No significant differences were seen in the mesorectal resection quality, CRM distance, distal resection margin (DRM) involvement, DRM distance, local R1 resection, intraoperative complications, morbidity, anastomotic leakage, severe morbidity, mortality, operative time, intraoperative blood loss, harvested lymph nodes, and local recurrence rate (P > 0.05).

Conclusion: The TaTME is a promising surgical technique and is fully a safe and efficacious option in managing low rectal cancer.

키워드

Laparoscopic surgery; Rectal cancer; Transanal endoscopic surgical procedures

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