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抗體産生에 미치는 Chloramphenicol 및 Cortisone의 影響

Influence of Chloramphenicol and Cortisone on Immunological Reaction of animals

이화약학회지 1968년 9권 0호 p.28 ~ 34
이정희, 최성남,
소속 상세정보
이정희 (  ) - 이화여자대학교
최성남 (  ) - 이화여자대학교

Abstract


It is observed that antibody production to heterologous antigen treated rabbit is inhibited by the certain kinds of drugs.
The titration and paper electrophoresis were checked in two groups at six period with four days interval and the drug was injected during the period of immunization.
(1) We used 10% sheep´s red blood cell as the heterologous antigen and injected rabbit´s ear vein.
(2) Chloramphenicol and cortisone were used and treated with intramuscular injection.
(3) The determination of immune response of rabbits to heterologous antigens were carried out by the method of Kolmer´s CF test and Paper electrophoresis.
(4) It was supposed that these drugs have decreasing effects about the antibody formation in rabbit.

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