잠시만 기다려 주세요. 로딩중입니다.

Metrazol 및 Picrotoxin 痙攣에 미치는 朝鮮人蔘及 Chlorpromazine의 影響

Influence of Panax Ginseng and Chlorpromazine on Metrazol-and Picrotoxin-convulsion

전남의대잡지 1964년 1권 1호 p.31 ~ 36
문영벽,
소속 상세정보
문영벽 (  ) - 전남대학교 의과대학 정신과교실

Abstract


It has been reported that Panax ginseng caused prolongation of hexobarbital-hypnosis and suppression of cocaine convulsion, suggesting some central effects of this crude drug. In the present study, employing frogs, it was attempted to examine whether metrazol-and picrotoxin-convulsion were affected by Panax ginseng.
The results of the present experiment showed that high doses of Panzx Ginseng definitedly suppressed onset of both metrazol-and picrotoxin-convulsion, but smaller doses had tendency to facilitate the onset of the metrazol-convulsion.
As it was reported by Deshpande et al.(1963)that metrazol-convulsion in the frog was potentiated by chlorpromazine, the effect of Panax Ginseng on these metrazol-chlorpromazine interactions was observed. The results were that the onset of metrazol-convulsion was markedly delayed when ginseng and chlorpromazine were administered together, i.e., the potentiating effect of chlorpromazine was blocked by Panax ginseng.

키워드

원문 및 링크아웃 정보

등재저널 정보