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家兎赤血球에 依한 Methemoglobin 還元에 미치는 Lactate와 Pyruvate의 影響

Effect of Lactate and Pyruvate on the Reduction of Methemoglobin by Rabbit Erythrocytes in vitro

전남의대잡지 1967년 4권 1호 p.123 ~ 126
김제권,
소속 상세정보
김제권 (  ) - 전남대학교 의과대학 정신과학교실

Abstract


The reduction of methemoglobin by rabbit erythrocytes in vitro was suppressed by the addition of pyruvate (8-10 nmM), and enhanced by lactate (28-58 MM).
It is suggested that the inhibitory effect of pyruvate on methemoglobin reduction might possibly be protected in vivo by the heart-type isozyme of lactate dehydrogenase which is predominant in normal mature erythrocytes and exhibits the property of being inhibited by high pyruvate concentration.

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