잠시만 기다려 주세요. 로딩중입니다.

Stein-Leventhal 徵候群에 있어서 Testosterone 産出率

Testosterone Production Rate in Stein-Leventhal Syndrome

전남의대잡지 1968년 5권 1호 p.115 ~ 122
허진득,
소속 상세정보
허진득 (  ) - 전남대학교 의과대학 내과학교실

Abstract


A thin layer chromatographic procedure, which is able to separate testosterone from epitestosterone and testosterone metabolites, was developed. Using this new procedure, the testosterone production rate was estimated in normal males and females, and females with hirsutism.
The testosterone production rate ranged from 5.9. to 8.0, mean 6.9 mg/d in 4 normal males and 0.7 to 1.5, mean 1.0 mg/d in 3 normal females. Hirsutism with elevated 17-ketosteroid did not show any significant elevation in testosterone levels, whereas two cases of Stein-Leventhal syndrome demonstrated markedly elevated production rates with normal urinary 17-ketosteroid. In a case of Stein-Leventhal syndrome, estrogen administration markedly suppressed the: testosterone production rate, while the urinary 17-ketosteroid remained unsuppressed.
The evidences presented above indicate that the origin-of the testosterone secretion in the cases of Stein-Leventhal is the ovary.

키워드

원문 및 링크아웃 정보

등재저널 정보