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家兎에 있어서의 Benemid의 利尿作用

Diuretic action of Benemid in the Rabbit

전남의대잡지 1968년 5권 1호 p.123 ~ 126
김은경,
소속 상세정보
김은경 (  ) - 전남대학교 의과대학 약리학교실

Abstract


The diuretic action of Benemid in the rabbit was investigated, and it was found that it elicits a marked diuresis during bicarbonate infusion whereas no diuresis ensues during infusion of hydrochloric acid & or sodium sulfate.
This action does not rest on the. change in glomerular filtration rate, but results from inhibition of reabsorption of electrolytes, in the tubule. It is postulated that Benemid inhibits carbonic anhydrase in the nephron.

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