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遺傳的 對側性色素異常症 (Dyschromatosis Symmetrica Hereditaria-Toyama)의 3症例報告와 文獻考察과 組織學的 新知見

Three cases of Dyschromatosis Symmetrica Heraditaria

전남의대잡지 1969년 6권 3호 p.517 ~ 523
김영표,
소속 상세정보
김영표 (  ) - 전남대학교 의과대학 피부과학교실

Abstract


Three have been some confusions and conflicts concerning the diagnosis of Dyschromatosis Symmetrica Hereditaria which has been called under different name by different authors. Nature of the disease is basically the same although clinical manifestation and involving areas of thee body surface is different.
Three different clinical manifestations of Dyschromatosis Symmetrica Hereditaria affected Korean are presented. The first type of Dyschromatosis Symmetrica Hereditaria is Toyama’s type which is characterized by showing various size of dark brown pigmented macular skin lesion over the face neck bark of hands and fed without subjective symptom. The second is Matsumoto’s type which is characterised by having pigmented and depigmented macular satin lesion usually seen in the areas where Toyama’s type are manifesting. The third is Tchikawa and Hiraga´s type which is characterised by showing both pigmented and depigmented mcular skin lesion over the entire body integument.
Histapathological characteristies of Dyschromatosis Symmetrica Hereditaria are consisted of hypgrkeratosis, increased melanin, granules in stratum mucosum of epidermis and swollen granular cells which seem to be in abnormal , keranization process and occasionally, keratotic pluggings otherwise no pathological change is found.
Review of literatures of Dyschromatosis Symmetrica Hereditaria and discussions in connection with the disease and heredity are also included.

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