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胃癌의 早期診斷에 關한 硏究

Studies on the Early Detection of Gastric malignancy

전남의대잡지 1970년 7권 1호 p.57 ~ 61
尹鍾晩, 朴玉圭, 李泰熙,
소속 상세정보
尹鍾晩 (  ) - 全南大學校 醫科大學 內科學敎室
朴玉圭 (  ) - 全南大學校 醫科大學 內科學敎室
李泰熙 (  ) - 全南大學校 醫科大學 內科學敎室

Abstract


According to a recent report of Odell, et al. the ribonuclease(RNAse) activity in vaginal fluid is closely related to the development of uterine malignancies.
In present study, enzymatic activity of the RNAse in gastric juice from five nonspecific, eight gastricr olcer and seven gastric cancer patients were measured for comparative purpose.
RNAse activity of gastric juice were 0.21±009 O. D. /mg, 0.12±0.12 O. D/ mg and 0. 16±0.09 O. D. /mg in gastric cancer patients; thus the RNAse activity appeared to be slightly decreased in ulcer and cancer patients, however, the statistical analysis of the results indicated nonsignificant in these limited groups
Further investigations are needed to find out a significance of RNAse activity for early detection of stomach malignancy; measuring RNAse activity off tumor tissue as well as the gastric juice under various intragastric conditions are necessary in more cases for this study.

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