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A Clinical Survey of Malignant Tumor of Nasal Cavity and Paranasal Sinuses
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KMID : 0376219730100010071
Abstract
Malignant Tumor arising from nasal cavity and paranasal sinuses is highly lethal disease often characterized by an insidious onset, protracted clinical course and reluctance to most forms of therapy.
The generally unsatisfactory response to treatment was attributed to a number of factors that included;
1) the complex anatomy of the region involved;
2) the advanced stage of the disease at the time of diagnosis;
3) the poor economic problems for therapy
Forty seven cases of primary cancer of nasal cavity and paranasal sinuses were observed at Dept. of Otolaryngology, Chonnam University Hospital from 1967through 1972.
The results may be summarized as follows:
1) The relative incidence is more common in male¢¥ than in female with the highest incidence occuring in the 4th decade of life.
2) Subjective complaints were purulent & /or bloody nasal discharge, swelling of cheek or face, headache, nasal obstruction, nasal mass, foul odor, exophthalmos and palpable neck node in order of frequency.
3) Duration of disease was 7 months in average.
4) Anatomic site of origin was maxillary antrum 25 cases(53.2%), nasal cavity 19 cases(40.4%) and ethmoid sinus 3 cases(6.4, %).
5) Histopathological finding revealed squamous cell carcinoma 30 cases(63.8 %), adenocarcinoma 7 cases(17%) and each 2 cases in anaplastic cancer, osteosarcoma and transitional cell cancer.
6) Treatmnent was refused or patient did not comeback in 14 cases and disease too far advanced for treatment in 12 cases. Partial and radical maxillectomy were performed in 18 cases, Three cases were administered external irradiation only.
7) The result was 22.2% five-year survival among a group of eighteen patients treated by combined methods. But three patients who treated by irradiation alone were died within 3 years.
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