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抗生劑 及 代謝抑制劑 Pyocyanin 及 Oxidase 産生에 미치는 影響

The Effects of Antibiotics and Enxyme Inhibitors on Pyocyanin and Cytochrome Oxidase Production of Pseudomonas Aeruginosa

중앙의학 1963년 4권 2호 p.143 ~ 147
朴商煥, 張元龍, 池重敏,
소속 상세정보
朴商煥 (  ) - 慶北大學校 醫科大學 細菌學敎室
張元龍 (  ) - 陸軍中央醫務試驗所
池重敏 (  ) - 慶北大學校 醫科大學 細菌學敎室

Abstract


In the previous communication, authors had studied the relation between pyocyanin production and oxidase formation of Pseudomonas aeruginosa, and it was found that the production of pyocyanin and oxidase are paralleled on the nutrient agar, but inhibted in media containing reducing agents.
In the present report, authors report the effects of antibiotics and enzyme inhibitors on pyocyanin and cytochrome oxidase produciton of Ps. aeruginosa.
The results are as follopws:
1. Of the antibiotics tesed, streptomycin and kanamycin markedly enhanced the pyocyanin producion, and erythromycin and Neomycin, on the other hand, inhibit the giment formation on the nutrient agar.
2. All the antibiotics, regardless of cincintration, inhibit the oxidase produciton.
3. KCN inhibit the pyocyanin produciton, while P-nitrophenol inhibit the exidase production in the broth culture.

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