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淋巴腫樣甲狀腺腫

Struma Lymphomatosa(Hashimoto´s Disease)

중앙의학 1963년 4권 6호 p.443 ~ 450
김순응, 賓注源, 申必秀,
소속 상세정보
김순응 (  ) - 延世大學校 醫科大學 病理學敎室
賓注源 (  ) - 延世大學校 醫科大學 病理學敎室
申必秀 (  ) - 延世大學校 醫科大學 病理學敎室

Abstract


Eight cases of struma lymphomatosa confirmed by operation and microscopic study are reported because of the paucity of the reports on this condition occurring among Koreans and to emphasize the awareness of this disease among clinicians, especially surgeons for the proper management of the patients with goiters.
These cases are found among 167 thyroid operations at the Severance Hospital, thus the incidence being 4.8%. All eight cases are found among female. The average age is 46 years, the youngest being 28 years and the oldest 59 years. The constant complaint is bilateral enlargement of the thyroid of firm and rubbery consistency. Dysphagia is predominent symptom and the others observed are tachycardia, palpitation and husky voice. The basal metabolic rates are within normal limit. In one case. in which carcinoma is suspected and subtotal thyroidectomy performed, the postoperative course is complicated with myxedema. The low incidence of r ostoperativemyxedema in this series is apparently due to inadequate follow-up.
The pathologic features, grossly and microscopically are described._ Diminution of size of follicles, depletion of colloid in most follicles, oxyphilic change of thyroid epithelium, marked lymphocytic infiltration, lymphoid follicles with germinal center, mild to moderate fibrosis are observed microscopically in all cases.

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