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Cortisone이 흰쥐 肝細胞分劃에 있어서의 Glutamin-pyruvic Transaminase活性에 미치는 影響

Effect of Cortisone on the Glutamin-pyruvic Transaminase Activity in the Subcellular Fractions of Rat Liver

중앙의학 1964년 6권 1호 p.59 ~ 61
李承澤, 朴明子,
소속 상세정보
李承澤 (  ) - 原子力硏究所
朴明子 (  ) - 原子力硏究所

Abstract


The authors have studied the subcellar distrubution of glutamic- pyruvic transaminase (GPT) activities in the normal and cortisone treated rat liver.The GPT activities in each fraction increased in the cortisone treated group.
According to the autors´ result the relative increment of the GPT activitity in the mitochomdrial fraction compare to that of in other fractions was not remarkable. The possible interpretation of this resrult was such that the effect of cortisone on mitochondrial fraction was less than on the other fractions, the reactien. alanine+α-glutamic acid-pyruvic acid+ glutamic acid was less active in this fraction.

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