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火傷 및 凍傷이 家兎 各臟器 組織內水分量 및 電解質分布狀態에 미치는 影響

Effect of Burn and Frostbite on Water and Electrolyte Distribution in Various Rabbit Tissues.

중앙의학 1964년 7권 6호 p.673 ~ 682
김용언,
소속 상세정보
김용언 (  ) - 서울대학교 의과대학 생화학교실

Abstract


Rabbits were subjected to burn and frostbite to study variations in the tissue electrolyte distribution, extracellular space and total Na +K.
Ninety animals were divided into 5 groups, 2 being burn injured, 2 frostbitten and 1 control.
Observations were carried out after 24 hours and 48 hours respectively in each experimental group by flame photometry and chemical methods.
The results were as follows;
1, Burn and frostbite effect a remarkable decrease in serum electrolyte.
2. Na and Cl increased in the liver of both burn and frostbitten groups, while K decreased in the liver of the former and increased in that of the latter groups.
3. Na increase and K decrease were effected in the kidney of both experimental groups.
4 Both Na and K decreased in the lung of each groups, while Cl increased in that of the frostbitten groups.
5. Water content increased in the skeletal muscle of both experimental groups suggesting a muscular edema.
Both Na and Cl increased in this tissue, but K decreased in both experimental groups.
6. The decrease in Na and increase in CI are common in the cardiac muscle of both experimental groups, but K increased only in that of the frostbitten groups,
7. All of the Na, K and Cl decrease in the brain and spleen of the both experimental groups, resulting in a low electrolytic condition.
In resume, burn and frostbite bring out an extremely low electrolyte contents in the serum effecting a hydremic condition to the animal. In the other tissues except the brain and spleen both Cl and Cl space increments are a ubiquitous effect in burn and frostbite, suggesting a possible relationship with tissue excitability.
Na and K variations antagonize in most cases and their specificities with respect to different tissues and stresses are noted, with all the effects being more accentauated at 48 hours than 24 hours after burn and frostbite.

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