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正常胃體部粘膜 특히 胃底腺 上皮의 細胞分裂에 關한 硏究

Studies on Cell Divisions in the Mucosal and Glandular Epithelium of the Body of the Stomach

중앙의학 1965년 8권 3호 p.281 ~ 285
유재훈,
소속 상세정보
유재훈 (  ) - 가톨릭대학 의학부 해부학교실

Abstract


In order to the clarify the many disputed problems concerning the renewal of ´the surface, foveolar and glandular epithelium of gastric mucosa, the mitotic and amitotic division of epithelial cells were observed in the stomachs of man, monkey, rabbit and mouse histologically. The results obtained from five cases are summarized as follows:
1. No cell division of any kind was observed in the surface epithelial cells of the gastric mucosa.
2. Mitoses were found only at the base of foveolae and the neck of the glands, composed of mucoid and undifferentiated cells known as the mother cell of the dividing cells,
3. Mitoses were found in the mouse stomach most frequently and in diminished number in the rabbit, monkey and man in that order. So the number of the mitotic cells in the vertical sections of 10mm mucosa averaged 81, 38, 27 and 11 respectively.
4. Multinuclear cells containing two to five or more nuclei of the same size, form and structure, as a result of amitosis, were found, in contrast to mitotic cells, commonly in the body or base of the gastric glands.
5. In the parietal cells, no mitotic figures were observed in any of the studies cases; the multinuclear varieties were found very often in human stomach, less frequently in monkey and rabbit, and scarcely in mouse stomach. Their number in 10mm vertical sections averaged 37, 27, 25 and 7, respectively.
6. In the chief cells, no mitoses occurred in any of the studied cases also, the multinuclear forms, which were probably overlooked by many investigators, could be found in all the cases in varying numbers, i.e, in the human gastric rmuucosa 6, in monkey 9, in rabbit 3 and in mouse 3 in 10mm vertical sections.

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