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토끼 고환의 저장철에 관한 연구

Studies on Testicular Storage Iron in rabbits

중앙의학 1968년 15권 6호 p.485 ~ 493
김형곤,
소속 상세정보
김형곤 (  ) - 부산대학교 의과대학 병리학교실

Abstract


The author investigated changes of storage iron concentration of testis after birth in immature rabbits and in mature rabbits. He observed, further, the effect of parenteral iron overload, massive withdrawals of erythrocyrtes, removal of pituitary body, thyroid gland or bilateral adrenals, and unilateral castration, vasectomy or heteotopic fixation of testis on the storage iron concentration of testis.
He analysed the data statistically and discussed the results thus obtained and came to the following conclusions:
1. The storage iron concentration of immature testis is lower than that of mature one, but as the testis grows, it increases its iron concentration and reaches the adult level at about 5 months after birth. The raw, mature, testicular tissue contains 1. 2mg. /100g of hemosiderin iron and 0.9mg/100g of ferritin iron on the average.
2. The storage iron concentration of testis has a tendency to increase in the rabbits parenterally given a larg does of colloidal iron, whereas it exhibits a tendency to decrease in the rabbits made severely anemic by repeated, withdrawals of massive blood cells.
3. The storage iron concentration of testis shows a mild decreasing tendency after bilateral adrenalectomy, while it is not affected by hypophysectomy or thyroidectomy.
4. Unilateral castration has an increasing effect on the storage iron concentration in the remaining testis.
5. The storage iron concentration is lower in the testis heterotopirally fixed in the peritoneal cavity, or undergone vasectomy than in its intact counterpart.
6. On the basis of the above, it is suggested that, the .testicular storage , iron may concern the testicular function proper rather than it takes a part in the erythropoiesis, as does the storage iron of the liver and spleen.

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