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콜레라菌의 抗生物質 vibriocin 生産

Production of Antibiotic Substances, Vibriocins, by Vibrio Cholerae Biotype El Tor

중앙의학 1970년 19권 4호 p.315 ~ 318
이영춘,
소속 상세정보
이영춘 (  ) - 전남대학교 의과대학 세균학교실

Abstract


Twenty-nine strains of Vibrio cholowe No type el for isolated from the cholera epidemic in Korea On September, 1969 were subjected to study on the production of vibriocin, employing ultraviolet-irradiated induction method.
Two strains of twenty-nine isolates tested were found to be vibriocin producers. The vibriocins, inhibited all of the seven indicator strains, received from K. L. Vos-ti, indicating the vibriocins exert a relatively wide range of antibacterial activity against Escherichia coli.
All two strains of vibriocinogenic vibrios were found to be inhibited by colicinogenic strains of Escherichia coli recently isolated from healthy persons and patients; one of the vibriocinogenic strains worm was inhibited by three kinds of colicin type (colicin B, E2, and unclassified) and other (HAVC-29) by one kind of colicin type (unclassified type). In other words, four strains among forty-one colicinogenic Escherichia coli inhibited two strains of vibriocinogenic vibrios.
Vibriocinogeny was briefly discussed in relation to pathogenesis of cholera.

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