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各種波長可視光線照射時의 正常白鼠의 好酸球數의 變動및 Chlorpromazine投與時의 影響

Influences of Various Visible Ray on the Eosinophile Count in Normal Rats, and Also in Kals Following Administration of Chlorpromazine

최신의학 1959년 2권 5호 p.11 ~ 16
申萬鍊, 丁東均,
소속 상세정보
申萬鍊 (  ) - 首都醫科大學 藥理學敎室
丁東均 (  ) - 서울대학교 藥理學敎室

Abstract


In the previous article, the authors described the fluctuations of 17-ketosteroid values in the rib bit urine after irradiation with various visible r ays, and the administration of chlorpromazine gives no change in the excretes of the substance. In this experiment, the author has observed the changing rate of eosinophiles by the irradiation of isolated rays and also the effects of chlorpromazine on the eosinophile count.
The reults are summerized as follows.
1. The irradiation of various visible rays caused a defenite decrease in the eosinophile count inthe rats. The blue ray, the shortest wavelength, has the strongest action of decreasing. while has the rad ray, the longest, the Ieast effect.
This suggests that the flashing of visible rays causes a dcfenite stress as would result in the decrease of eosinophile count.
2. There showed no significant difference in the decrease of eosinophile count between the normal rats treated with chlorpromazine and the control rats flashed with normal ray.
Therefore, this could demonstrate that chlorpromazine can block the stress action caused by the light.

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