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所謂 性中樞에 關한 實驗的 硏究

Experimental Studies on the "Sex Regulating Center"

최신의학 1959년 2권 6호 p.11 ~ 28
이한규,
소속 상세정보
이한규 (  ) - 수도의과대학 산부인과학교실

Abstract


Recent experiments suggest that the sex regulating center may be located in the hypothalamic region. The purpose of this investigation is to confirm the center per se and, in addition, to characterize its function further. Also it is the contention of this author that the present study will define some knowledges on central regulation of sex function, with the hope that this will give aid to the current hormonal therapy. The responses of reproductive organs following physical or chemical stimuli on hypothalamic regions are thus investigated.
The apparatus used in this study are made by this author. The vaginal smear for esterous cycle, appearance of ovulation, and histological changes of ovary or uterus are the main observations for this investigation.
The results obtained after the application of such stuimuli as light. electricity or chemicals on hypothalamic regions are summerized as follows:
1. Pertinent esterous of 15-8 days are shown in all (8 rats) Kept under the light stimuli (electrical florescence bulb.)
Following the chiorpromaz:ne treat-ncm. the above rats ceased the esterous for 33--20days. It is felt that the influence of the light stimuli on sex function may be mediated through the optic nerve to hypothalamus, anterior pitutitary, and consequently to sex glands. This results, especially with chlorpromzine, is consistent with those obtained by Brown, Benoit, Dempsy, Eventte 2nd others. Particulary, author´s experiment with chlorpromazine stieng then their results.
2. The effects on sex function of direct electrical stimulation of hypothalamic regions are followings:
a) Rats received the stimuli on the infundibulum show a noticable pertient esterous and histological si;n of livperactivity of both the ovary and uterus.
b) Rats received the stimuli on both the infundibu um and the optic chiasm show a slighter increases in esterous and also show slighter hyperactivity on both the ovary and uterus, as compared wita the control.

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