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마우스 去勢로 因한 所謂 去勢前葉 成立과 이에 對한 Chlorpromazine投與에 依한 影響

Establishment of so called "Casterized Anterior Lobe" by Castration of the Mouse and Influence of Chlorpromazine Administration on it

최신의학 1960년 3권 9호 p.101 ~ 104
민충현,
소속 상세정보
민충현 (  ) - 수도의과대학 산부인과학교실

Abstract


1Q Histological findings of anterior lobe of normal mouse compose of 3 kinds of cells, i. e. main, eosinoephilic and basophilic cells. Their number and distribution show that the main cells are most prominent in number and every distributed throughout anterior lobe. The next is eosiuophilic cells and basophilic cells are very few.
(9 The specific changes of anterior lobe by casterization are marked proliferation and hypertrophy of basophilic cells. Above specific change, so called the figure of Casterized anterior lobe can be demonstrated in the anterior lobe of mouse 30 days after casterization.
QAbove so called the phase of Casterized anterior lobe is markedly arrested by administration of Chlorpromazine.
O Abovesuggested that the establishment of Casterized anterior lobe is not direct reaction of anterior lobe by casterization, but hypothalamus reacted first to deficency of steroids by casterization and next it gave accelerating stimulation to anterior lobe.

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