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胎兒 損失防止를 爲한 合成 黃體홀몬劑 Norlutin, Delautin, Enovid의 作用에 關하여

Progesterone-like Hormones Norlutin, Delaution, Enovid for Prevention of Fetal Loss

최신의학 1962년 5권 10호 p.101 ~ 104
이기영,
소속 상세정보
이기영 (  ) - 경북대학교 의과대학 산부인과학교실

Abstract


1. This study is to give the results of patients previously aborted who were treated with Norlutin, Delalutin, and Enovid.
2. The patients who previously aborted include two groups; one treated with hormones and the other treated without hormones.
3. The control group of 5,507 had a fetal salvage of 87.6%; 10.4% abortions up to 22 week and 2% fetal loss in the last part of pregnancy.
4. The abortion and fetal loss rate increased from 9.3% to 21.6% to 69% to 92% with each additional previous pregnancy loss. The fetal loss in the last 4 months of gestation increased from 1.8% to 2.7% to 6.2% with each additional previous abortion.
5. All three progesterone-like hormones are excellent in preventing abortion. In this study Enovid proves superior in the last half of pregnancy.
6. The fetal salvage is greatly improved in the hormone treated groups, compared to the control group.
7. Complications and side effects were very low in women treated with progesterone-like hormones. One hormone caused transitory masculinizing effect in the mothers and enlargement of the clitoris in two female infants.
8. The results using progesterone-like drugs in previous aborters is sufficiently valuable to warrant its further use.

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