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精密溫度測定에 依한 胃粘膜血流量變化의 推定에 關한 硏究

Estimation of Blood Flow Changes of Gastric Mucosa by Measurement of Local Temperature in Dog and Human

최신의학 1964년 7권 6호 p.59 ~ 67
우원형,
소속 상세정보
우원형 (  ) - 경북대학교 의과대학 방사선과학교실

Abstract


An intragastric thermistor thermometer was devised for the determination of the temperature in the living gastic mucosa. One or. two, very small Fenwal thermistors were fitted onto the inner surface of latex rubber balloon and were connected by means of fine lead electric wire to the amplifier and galvanometer through the bigger hole of the Miller-Abbott tube. This tube was inserted into the stomach through the esophagus and was positioned as to fix its tip in the pyloric canal.
All experiments were carried out under fluoroscopic control to ascertain the degree of distension of balloon and the position of thermistors. The thermistors were attached to the lesser and/or to the greater curvature side of the mucosa. Four different degrees of inflation of the balloon were graded ´minimal,´ ´moderate´, ´marked´ and ´extreme´ in the dog and ´minimal´. ´moderate´ and ´marked´, in the human subjects. The temperature was determined in the following different positions; (1) supine. (2) supine and left lateral and (3) supine and right lateral in dogs and supine position only in human subjects.
The difference in temperature of the gastric mucosa between minimal distension and the other degrees of distension were compared and the following results were obtained.
1. The volume of blood flow of the gastric mucosa by the distension of the stomach was estimated qualitatively by the fall in temperature. In a total of 22 cases of dog in the supine position the mean of fall in temperature of the gastric mucosa in the lesser curvature side when increasing the degree of distension from minimal to moderate, to marked and to extreme was 0.070.021 C(P< 0.01), - 0.17+10.029C(P(0.001), and 0.290.035C(P(0.001) respectively: And on the greater curvature side the mean fall was 0.01+0.016C(P< 0.6), 0.04+0.019C(P< 0.05) and 0.0+ 0.018C(P< 0.01) respectively.
2. In 34 cases of the human subjects in the supine position, a significant change of fall in temperature was noted particularly on the gastric mucosa of the lesser curvature when the stomach was subjected to various degree of distension.
3. It is felt that the marked fall in temperature of the _gastric mucosa of the. lesser curvature as compared with the greater curvature, may be attributed to inherently abundance of the blood flow following distension of the stomach. This fact possibly explains why the gastric cancer, ulcer or the other gastric diseases occur more likely at the lesser curvature side: than greater curvature side.

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