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男子不妊症

Male Infertility

최신의학 1967년 10권 8호 p.65 ~ 73
이희영,
소속 상세정보
이희영 (  ) - 서울대학교 의과대학 비뇨기과학교실

Abstract


A statistcal survey was undertaken on male infertility patients who were seen in the Department of Urology College of Medicine, Seoul National University, during the period frcm Jan. 13 5 to Dec. 1966 and the following results were obtained.
1. Primary sterility is found in 82 per cent of the total infertile males and the secondary, 18 per cent.
2. Total 431 cases of male infertility occupy 1.72 per cent of total urolegical outpatients(25,123 cases), and correspond to 2.0 per cent of total male outpatients(21,592 cases) for the period of 12 years.
Incidence of male infertility is increasing year by year with ;,the ratio from 2.3 per cent in 1955 to 22 per cent in 1966(Table 1, and Fig. 1).
3. Age of male sterility cases varies from 24 to 61, the median being 35.8, and that of their wives ranges from 24 to 49, the median, 32(Table 2).
4. Duration of sterile marital life ranges frcm 1 to 40 years, the median being 9 years. An average duration of the sterility cases who were seen between 1955 to 1960 indicates 10 years but that of the cases who were seen between 1961 to 1966 shows 8 years(Table 3, and Fig. 2).
5. Occupations of the infertile males comprise merchants, farmers, government officers, company employees, laborers, teachers, soldiers, and engineers. Of these, mental laborers are 116 cases and muscular laborers, 203 cases. There are no correlations between the incidence of male infertility and their occupations(Table 4).
6. Suspective etiological factors and major past illness with the male infertility are as follows: gonorrheal epididymitis(22.76 % ), testicular hypoplasia(16.68%), vasectomized men who are wanting to have recanalization(6.96%), tuberculous epididymitis(4.18%), nonspecific epididymitis(2.32%), injuries of seminal tracts (1.84%), eunuchoidism(1.62%), cryptorcbidism(1.16%), varicocele(0.7%), mumps orchitis(0.7%), hematospermia(0.7 % ), hydrocele(0.46 % ), absence of vasa(0.46 % ), Klinefelter´s syndreme(0.46%), incompatibi lity of semen(0.23%), and causes unknown including oligospermia and azoospermia(30.86%)(Table 5).
7. According to etiological classifications, faulty spermatogenesis occupies 46.6 per cent of the total cases; faulty sperm, transportation, 24.1 per cent; faulty seminal composition, 11.6 per cent and unknown causes, 9.7 per cent, respectively(Table 6).
8. Judging from the results of semen analyses, azoospermia is found in 50.8 per cent, oligospermia, in 31.6 per cent and normospermia, in 9.7 per cent of the 397 cases in whom semen was examined. In twenty five patients, semen analysis reveals normal, but no babies havebeen born within 3 years of normal marital life even with fertile women. No primary causes are found in 15.31 per cent of oligospermia, in 9.74 per cent of azoospermia and in 25 cases of normospermia(Table 7).
9. An average value of semen analyses is as follows: volume was 2.75 ml.; counts per ml., 90.2 millions,;motility, 63.7 par cent and normal shape, 83 per cent in normospermic groupi - vvhele volunme´ was -2.9 ml.,. count, 19.9 millions; motility, 30.8 per cent and normal shape, 66.4 per cent, respectively, in oligospermic group(Table 8).
10. Findings of testicular biopsies of awospermics show that germinal cell aplasia was 48 per cent; germinal cell arrest, 20 per cent; generalized peritubuiar firosis, 8 per cent and occlusion or absence of efferent ducts, 24 per cent of the 66 awospermics(Table 9).
11. The average frequency of sexual intercourse of the sterility group shows 2.08 per week while that of the fertile normal group indicates 2.18 per week with no signeficant differences between the sterile group and the
fertile group(Table 10).

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