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Dipterex의 蛔蟲驅蟲 效果 및 毒性實驗

Clinical Trial of Dipterex on the Infection of Ascaris lumbricoides

최신의학 1967년 10권 11호 p.93 ~ 95
간정민, 최길준, 김옥천, 이재흥,
소속 상세정보
간정민 (  ) - 연세대학교 의과대학 기생충학교실
최길준 (  ) - 연세대학교 의과대학 기생충학교실
김옥천 (  ) - 연세대학교 의과대학 기생충학교실
이재흥 (  ) - 연세대학교 의과대학 기생충학교실

Abstract


The effect of Dipterex: 0,0-dimethyl 2, 2, 2-trichloro-l-hydroxyethyl phosphonate on 106 cases of ascaris infection was investigated. The drug was given for two days with the doses of 15-20 mg/kg daily. The results are summarized as follows:
1. 62.3% of the cases passed all of their ascarides as a result of the treatment and the egg count reduction was 94.3%.
2. Mild xromiting was observed in a few cases just after the drug administration.
3. Hematology, blood chemistry and urinaalysis Were done in 6 cases before and after the drug administration and no abnormal finding was observed.
4 The drug was given to two dogs with the doses of 20 mgkg, 70 mg/kg respectively, but no pathological finding in liver lung and intestine was observed.

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