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下空靜脈移植에 關한 實驗的 硏究

An Experimental Study on Inferior Vena Cava Graft

최신의학 1968년 11권 11호 p.31 ~ 45
손광현,
소속 상세정보
손광현 (  ) - 서울대학교 의과대학 흉부외과학교실

Abstract


HemAyaaml c, roentgenological and histological study was carried out on inferior vena Cava replacement with fresh autogenous abdominal aortic graft in 30 dogs. The defect of the host´s aorta was bridged by ethyl j alcohol preserved homologous aorta.`
In the first group, of fifteen dogs supple inferior vena caval
graft was done. And in the second group of the fifteen dogs femoral arteriovenous fistula was created after caval replacement.
In the long term survivors results on graft patency rate, cavography. venous pressure and histological findings were compared. The period of observation on long term survivors ranged from one to five months. 1. Venous pressure
1. Post-graft venous pressure increase was significant but not remarkable.
2. AN fistula group showed significant venous pressure increase but not remarkable.
j(. Cavography
1. Complete patency rate was markedly greater in group U than group 1(57% to 25%).
2. In stenotic or occluded animals abundant collaterals were noted.
DI . Macroscopic findings of the specimens were obtained one, two, three, four, and five months after grafting respectively. Complete thrombotic occlusion rate was much greater in group 1 than II (75% to 29%).´
IV. Microscopic findings
1. No differences in repairing process of the graft were noted between these two groups.
2. In the early post operative months inflammatory reaction and repairing process were noted simultaneo-
usly. With the elapse of time repaying process was advanced and matured progressively.
3. By three months endothelialization of the intima was almost completely established.
V. Patency rate of the graft in A-V fistula group seemed to be favorably influenced by increased venous flow.

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