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Epinephrine 및 Prednisolone이 Arthus Reaction에 미치는 효과

Effect of Epinephrine and Prednisolone on Arthus Reaction

최신의학 1968년 11권 12호 p.49 ~ 59
최영철,
소속 상세정보
최영철 (  ) - 부산대학교 의과대학 외과학교실

Abstract


The author investigated, using rabbits, the effect of epinephrine and prednisolone on Arthus reaction. The animals were sensitized by repeated, intravenous or intraperitoneal injections of egg-albumin over a period of 4 or 5 Nveeks. The highly sensitized animals then were injected intradermally with the mixture of egg-albmin and epinephrine or prednisolone or egg-albumin alone within a few hours following a single systemic administration of epinephrine or prednisolone.
The results thus obtained were discussed and the conclusions drawn therefrom axe as follows:
1. The Arthus reaction was_intensified by the local or systemic administration of epinephrine.
2. The Arthus reaction was depressed by the local or systemic administration of prednisolone.

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