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Dilantin Sodium 投與로 因한 口腔粘膜 肥大症의 臨床 및 實驗的 硏究

Experimental Study of Dilantin sodium on Rats Oral Mucosa

최신의학 1970년 13권 2호 p.75 ~ 79
문동선,
소속 상세정보
문동선 (  ) - 서울대학교 의과대학 부속병원 치과

Abstract


After subcutaneous injections of 100mg/kg body weight of dilantin sodium to rats, the author observed following results.
1) Keratinization of oral mucous epithelium was highly increased.
2) Connective tissue of oral mucosa showed elevated fibroblastic activity with pronounced collagen fiber formation.
3) Histochemical staining reactions suggested a substitution of glycoproteins for mucopolysaccharides staining material in the connective tissue was noted.
4) Increase in the glycoproteins and mucopolysaccharides staining material in the connective tissue was noted.

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