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健康人의 血淸鐵, 鐵結合能 및 transferrin saturation 測定에 關하여

Determination of Serum Iron, Iron-Binding Capacity and Transferrin Saturation in Health.

한국영양학회지 1970년 3권 3호 p.141 ~ 147
채범석,
소속 상세정보
채범석 (  ) - 서울대학교 의과대학 임상병리학과

Abstract


Nutritional anemias are an important nutritional problem affecting large population groups in most developing countries. Many reports on investigations of nutritional anemias have been published and there is good evidence that prevalence of iron deficiency anemias in vulnerable groups is high in many areas of the world.
However, there is a general lack of accurate data on its prevalence throughout the world. Methods used to measure different factors have been variable and often of poor quality. Furthermore recent comparison of values obtained in different laboratories have shown a much greater discrepancy in iron binding capacity measurements as compared with serum iron determinations. Since the major
cause of these differences appears related to the technique employed, the efforts of the central laboratory will be directed initially to standardization of methodology. My laboratory has been joined interlaboratory comparison of WHO studies of iron standardization.
The determination of serum iron, iron-binding capacity and transferrin saturation was done on healthy adults, 79 males and 20 females, who visited hospital for health certificate from January to July 1970.
The serum iron was determined by the method of modification of Bothwell and Mallett and total iron binding capacity by Ramsay method and Bothwell and Mallett method.
The results of this study are as follows;
1) The serum iron concentration of seventy nine adult male by the method presented is 131.537.3 ug/100mL (range 52.5~225.OUg/100ml) and of twenty female adult is 108.540.2ug1100 ml (range 45.0^202. 5ug/100ml).
2) The adult male level of serum iron-binding capacity is 330. 948. 9ug/100ml and adult female is 291.255.2ug/100ml.
3) The transferrin saturation of healthy male is 35. 6-=12. 8% (range 15. 1~18. 0%) and of female as 25. 412. 4% (range 10. 1^60. 0016).

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