인후루엔자의 화학요법
CHEMOTHERAPY OF INFLUENZA
한국의과학 1970년 2권 3호 p.53 ~ 57
이기환,
소속 상세정보
이기환 ( )
한국의과학연구소 부속성심병원 내과
KMID : 0381219700020030053
Abstract
Influenza must be viewed primarily as an acute infectious, respiratory disease which is highly transmissible and commonly occurs in epidemic form.
The symptoms are characterized by fever, chills, headache, general aches and other multiple complaints. Uncomplicated influenza which is an acute febrile illness usually lasts for three or four days; however it develops infrequently into fetal complications such as pneumonia, myocarditis or encephalitis.
The treatment of influenza still remains only with symptomatic measurement. Therefore close medical attention should be directed toward the patient´s comfort with the use of analgesics, mild sedatives, adequate fluids and antibiotics against possible secondary bacterial infections.
Recently several kinds of antiviral compounds have been developed for the treatment of influenza, and they are not merely virucidal, but are capable of blocking or slowing viral penetration into the host cells or of suppressing proliferation of virus within the ´ host cells. And antiviral compounds such as adamantanamine hydrochloride, rimantadine hydrochloride and ABOB are known to have significant effect on the prevention of infection and shortenting the course of the illness.
This paper shows the review of literatures on the antiviral compounds as to their mechanism of antiviral action, the results of therapy and their toxicity.
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