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第Ⅱ篇 Positive Radial Acceleration Stress 下의 「마우스」의 心電圖

Studies of Positive Radial Acceleration on Mice Behavior, Survival Curve, Fatal Curve, Dangerous Zone, Mortality and Effects of Anti-g Suits

항공의학 1956년 4권 1호 p.22 ~ 31
정성장,
소속 상세정보
정성장 (  ) - 항공의학연구소

Abstract


Electrocardographic record of five normal adult mice were taken during the exposure to plus 20 g for 25 minutes by means of mercury slip rings.
An Electric centrifuge was used to produce g-force. All animal died as a result of the exposure.
From the ECG findings conclusions as follows were obtained.
1). In exposure to plus 20g asystole to three seconds occurs and the amplitude of S-waves continues to increase. In this period unknown waves (U-wave ?) appear with a long duration.
2). Chief ECG changes during exposures to large positive acceleration stress are a3 follows.
a) Pulse rate (ventriculas rate) gradually decreases. Then pulse frequently disappears and severe bradycardia follows.
At last the pulse disappears again and death occurs.
b) P. wave : decrease of amplitudes, negative and diphasic changes of forms of waves occur.
Its duration is first unchangeable and next shortens during the period when asystole occurs. It prolongs thereafter.
c) P-R interval prolong.
d) QRS-complexes : amplitudes of R-waves continue to decrease. Particularly, continuous increase of amplitudes of S-waves is most marked.
The duration of QRS-complexes prolongs.
e) T-waves : amplitudes first decrease and next markedly increase in the middle period when asytole occurs. Thereafter they gradually decrease again
f) Q-T interval prolongs.
3). Considering the ECG changes of mice exposed to positive acceleration, the heart of mice is relatively resistant to positive radial acceleration stress.

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