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천식음이 동반된 Bronchiolitis Obliterans Organizing Pneumonia 1예

A Case of Bronchiolitis Obliterans Organizing Pneumonia Associated with Wheezing

결핵및호흡기질환 1993년 40권 6호 p.730 ~ 735
소속 상세정보
이재석/Jae Seok Lee 김도진/안영수/이상무/김현태/어수택/김용훈/박춘식/Do Jin Kim/Young Soo Ahn/Sang Moo Lee/Hyeon Tae Kim/Soo Taek Uh/Yong Hoon Kim/Choon Sik Park

Abstract

요약
최근 저자들은 스테로이드에 잘 반응하나 재발을 잘하고 천명음이 동반된 BOOP 1예를
경험하였기에 문헌고찰과 함께 보고하는 바이다.
#초록#
BOOP is a clinopathologic entity consisting of a flu-like illness, late inspiratory
crackles, and pathologically granulation tissue plugs within lumens of small airways
sometimes with complete obstruction of small airways and granulation tissue extending
into alveolar ducts and alveoli with a variable degree of interstitial infiltration of
mononuclear cells and accumulation of foamy macrophages in alveolar spaces in a patch
distribution, and preservation of Background architecture of the lung. It has patch
infiltrates roentgenographically, and restrictive ventilatory defect pysiologically such as
decreased vital capacity and diffusing capacity.
The BOOP has been observed in the context of collagen vascular disease, and other
autoimmune disease secondary to treatment with penicillamine, bleomycin, acebutolol and
amiodarone, following the inhalation of toxic fumes, after several infections including
measles, pertussis and influenza and idiopathic. Clinically, response to coricosteroid
therapy is good and relapse dose not occur if sufficient theraphy is good. A flu-like
illness occurs in one third, cough in one third, cough with dyspnea in the remaining
patients. Hemoptysis are rare. The physical examination reveales dry crackles in the
majority of the patients with BOOP but rarely associated with wheezing. The duration
of illness is less than 2 months in 75% of patients. With a brief review of literature, we
report a case of the BOOP which is good response to steroid, but frequent relapse and
assoicated with wheezing.

키워드

BOOP; Wheezing;

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