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원발성 폐육종 1예 : 이상성 활막육종(Biphasic Synovial Sarcoma)

A Case of Primary Pulmonary Sarcoma with Morphologic Features of Biphasic Synovial Sarcoma

결핵및호흡기질환 1998년 45권 6호 p.1284 ~ 1289
소속 상세정보
송소향/So Hyang Song 이관형/오정환/문화식/송정섭/박성학/김경미/이안희/Kwan Hyung Lee/Jeong Hwan Oh/Hwa Sik Moon/Jeong Sup Song/Sung Hak Park/Kyoung Mee Kim/Anhi Lee

Abstract

요약
저자들은 59세 여자환자에서 조직학적으로 면역학적으로 이상성 활막육종의 형태를 가진
원발성 폐육종 1예를 경혐하였기에 이를 문헌 고찰과 함께 보고하는 바이다.
#초록#
Synovial sarcoma is a malignant soft tissue neoplasm that occurs frequently in the
extremities of young adults, near large joints. The lung is a common site of metastasis
but an extremely unusual primary site for synovial sarcoma. We report an unusual case
of primary synovial sarcoma that arose in the lung of a 59-year-old woman. The tumor
had histologic and immunophenotypic features consistent with biphasic synovial sarcoma.
These features included of an intimate admixture of cytokeratin and epithelial membrane
antigen(EMA)-positive neoplastic epithelial cells and vimentin-positive fibroblast-like
spindle cells. The patient had a closed thoracomy drainage and doxycycline pleurodesis
for malignant loculated effusion and showed tumor extension in the left whole lung 4
months after pleurodesis. This case is an usual addition to the small number of
published reports on primary pulmonary synovial sarcoma. The distinctive features of
this neoplasm allow it to be distinguished from a variety of primary and metastatic
malignancies in the lung.

키워드

Biphasic synovial sarcoma; Lung tumor; Cytokeratin; EMA; Vimentin;

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