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간세포암종 환자에서 경동맥화학색전술 후 발생한 담낭 천공 1예

Gallbladder Perforation after Transarterial Chemoembolization in a Patient with a Huge Hepatocellular Carcinoma

대한소화기학회지 2020년 75권 6호 p.351 ~ 355
손민영 ( Son Min-Young ) - Kosin University College of Medicine Department of Internal Medicine

한병훈 ( Han Byung-Hoon ) - Kosin University College of Medicine Department of Internal Medicine
이상욱 ( Lee Sang-Uk ) - Kosin University College of Medicine Department of Internal Medicine
윤병철 ( Yun Byung-Cheol ) - Kosin University College of Medicine Department of Internal Medicine
서광일 ( Seo Kwang-Il ) - Kosin University College of Medicine Department of Internal Medicine
허진도 ( Huh Jin-Do ) - Kosin University College of Medicine Department of Radiology

Abstract


Transarterial chemoembolization (TACE) is a common treatment for unresectable hepatocellular carcinoma (HCC). The most common complications after TACE are non-specific symptoms called post-embolization syndrome, such as abdominal pain or fever. Rare complications, such as liver failure, liver abscess, sepsis, pulmonary embolism, cholecystitis, can also occur. On the other hand, gallbladder perforation is quite rare. This paper reports a case of gallbladder perforation following TACE. A 76-year-old male with a single 9-cm-sized HCC underwent TACE. Five days after TACE, he developed persistent right upper quadrant pain and ileus. An abdomen CT scan confirmed gallbladder perforation with bile in the right paracolic gutter and pelvic cavity. Percutaneous transhepatic gallbladder drainage was performed with the intravenous administration of antibiotics. After 1 month, the patient underwent right hemihepatectomy and cholecystectomy. Physicians should consider the possibility of gallbladder perforation, which is a rare complication after TACE, when unexplained abdominal pain persists.

키워드

Gallbladder; Rupture; Chemoembolization, therapeutic; Carcinoma, hepatocellular
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