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Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection

대한소화기학회지 2020년 76권 3호 p.159 ~ 163
이상훈, 이성준, 박성철, 남승주, 강명호, 김태석, 이승구,
소속 상세정보
이상훈 ( Lee Sang-Hoon ) - Kangwon National University School of Medicine Department of Internal Medicine
이성준 ( Lee Sung-Joon ) - Kangwon National University School of Medicine Department of Internal Medicine
박성철 ( Park Sung-Chul ) - Kangwon National University School of Medicine Department of Internal Medicine
남승주 ( Nam Seung-Joo ) - Kangwon National University School of Medicine Department of Internal Medicine
강명호 ( Kang Myeong-Ho ) - Kangwon National University School of Medicine Department of Internal Medicine
김태석 ( Kim Tae-Suk ) - Kangwon National University School of Medicine Department of Internal Medicine
이승구 ( Lee Seung-Koo ) - Kangwon National University School of Medicine Department of Anatomic Pathology

Abstract


Serrated polyposis syndrome (SPS) can transform to malignant lesions through the sessile serrated pathway and traditional serrated pathway. These pathways may cause rapid neoplastic progression compared to the adenoma-carcinoma sequence, which may cause interval colorectal cancer. The authors experienced a case of SPS with a synchronous colon adenocarcinoma that was treated with an endoscopic mucosal resection. In pathology reviews, other parts of the adenocarcinoma showed sessile serrated adenoma. Therefore, patients with SPS have a potential for malignant transformation, highlighting the need for strict colonoscopy surveillance starting at the time of SPS diagnosis.

키워드

Intestinal polyposis; Adenocarcinoma; Endoscopic mucosal resection

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