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성차의학 연구: 어떻게 할 것인가?

How to Study the Sex and Gender Effect in Biomedical Research?

대한소화기학회지 2021년 77권 3호 p.104 ~ 114
이문영, 김의중, 김용성,
소속 상세정보
이문영 ( Lee Moon-Young ) - Wonkwang University School of Medicine Department of Physiology
김의중 ( Kim Eui-Joong ) - Wonkwang University School of Medicine Department of Physiology
김용성 ( Kim Yong-Sung ) - Sanbon Good Breath Clinic

Abstract


Men and women are different, but this difference has not been well reflected in clinical trials and preclinical studies of biomedical science. Gender medicine, which systematically analyzes research results according to sex and gender, has been emphasized to overcome this problem. On the other hand, researchers still have difficulty in applying gender medicine to their research. To perform rigorous gender medicine, using correct terms, a thorough literature review during research planning, appropriate statistical analysis and reporting, and cautious interpretation of the results are necessary. Applying gender medicine will increase the reproducibility of studies, promote discoveries, expand the study relevance, and ultimately improve patient care in both men and women. Here, this study reviewed the practical issues on applying gender medicine to both preclinical and clinical studies in the field of biomedical science.

키워드

Sex; Gender equity; Translational medical research; Clinical trial

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