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바터팽대부암의 치료 Treatment of Ampullary Adenocarcinoma

대한소화기학회지 2023년 82권 4호 p.159 ~ 170
신동우,
소속 상세정보
신동우 ( Shin Dong-Woo ) 

Abstract


The ampulla of Vater is a small projection formed by the confluence of the main pancreatic duct and common bile duct in the second part of the duodenum. Primary ampullary adenocarcinoma is a rare malignancy, accounting for only 0.2% of gastrointestinal cancers and approximately 7% of all periampullary cancers. Jaundice from a biliary obstruction is the most common symptom of ampullary adenocarcinoma. In the early stages, radical pancreatoduodenectomy is the standard surgical approach. On the other hand, no randomized controlled trial has provided evidence to guide physicians on the choice of adjuvant/palliative chemotherapy because of the rarity of the disease and the paucity of related research. This paper reports the biology, histology, current therapeutic strategies, and potential future therapies of ampullary adenocarcinoma.

키워드

Ampulla of Vater; Adenocarcinoma; Chemotherapy; Radiotherapy

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