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헛개나무열매 열수추출물 투여에 의한 흰쥐의 지구력 향상 효과

Improvement in Exercise Endurance by Hovenia dulcis Fruit Hot Water Extract in Mice

한국식품영양학회지 2020년 33권 4호 p.363 ~ 371
권태형, 한준희, 이선엽, 유근형,
소속 상세정보
권태형 ( Kwon Tae-Hyung ) - Chuncheon Bio-industry Foundation Department of Research and Development
한준희 ( Han Joon-Hee ) - Chuncheon Bio-industry Foundation Department of Research and Development
이선엽 ( Lee Sun-Yeop ) - Chuncheon Bio-industry Foundation Department of Research and Development
유근형 ( Yu Keun-Hyung ) - Chuncheon Bio-industry Foundation Department of Research and Development

Abstract


This study was designed to evaluate the improvement in exercise endurance by Hovenia dulcis fruit hot water extract (HDWE) for the potential application as a functional food material. The effect was based on the evaluation of the forced-swimming capacity and changes in biochemical parameters in mice. Six-week-old mice were classified into four groups based on a randomized block design: the negative control group, the HDWE 50 mg/kg body weight group, the HDWE 200 mg/kg body weight group, and the 1-octacosanol 50 mg/kg body weight group (n=8 mice per group). The swimming exercise time in the HDWE-50 group was increased at 545±43 sec compared to the control group at 263±28 sec. The HDWE-200 fatigue indicators, lactate acid and ammonia content, decreased to 4.99±0.33 mg/mL and 0.63±0.05 mg/mL, respectively. In addition, the content of glycogen in the liver and muscle tended to increase in the group administered HDWE but was not significant. Likewise, the LDH and glucose contents were increased compared to the control group. The muscle damage indicators ALT (52.7±2.6 U/L) and AST (42.5±5.2 U/L) tended to decrease compared to the control group (76.4±10.2 U/L).

키워드

Hovenia dulcis; hot water extract; in vivo; endurance; antifatigue

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