잠시만 기다려 주세요. 로딩중입니다.

Additional Value of Integrated 18F-FDG PET/MRI for Evaluating Biliary Tract Cancer: Comparison with Contrast-Enhanced CT

Korean Journal of Radiology 2021년 22권 5호 p.714 ~ 724
Yoo Jeong-In, 이정민, 윤정희, 주이진, 이동호,
소속 상세정보
 ( Yoo Jeong-In ) - Seoul National University Hospital Department of Radiology
이정민 ( Lee Jeong-Min ) - Seoul National University College of Medicine Department of Radiology
윤정희 ( Yoon Jeong-Hee ) - Seoul National University College of Medicine Seoul National University Hospital Department of Radiology
주이진 ( Joo I-Jin ) - Seoul National University College of Medicine Seoul National University Hospital Department of Radiology
이동호 ( Lee Dong-Ho ) - Seoul National University College of Medicine Seoul National University Hospital Department of Radiology

Abstract


Objective: To evaluate the value of 18F-fluorodeoxyglucose PET/MRI added to contrast-enhanced CT (CECT) in initial staging, assessment of resectability, and postoperative follow-up of biliary tract cancer.

Materials and Methods: This retrospective study included 100 patients (initial workup [n = 65] and postoperative follow-up [n = 35]) who had undergone PET/MRI and CECT for bile duct or gallbladder lesions between January 2013 and March 2020. Two radiologists independently reviewed the CECT imaging set and CECT plus PET/MRI set to determine the likelihood of malignancy, local and overall resectability, and distant metastasis in the initial workup group, and local recurrence and distant metastasis in the follow-up group. Diagnostic performances of the two imaging sets were compared using clinical-surgical-pathologic findings as standards of reference.

Results: The diagnostic performance of CECT significantly improved after the addition of PET/MRI for liver metastasis (area under the receiver operating characteristic curve [Az]: 0.77 vs. 0.91 [p = 0.027] for reviewer 1; 0.76 vs. 0.92 [p = 0.021] for reviewer 2), lymph node metastasis (0.73 vs. 0.92 [p = 0.004]; 0.81 vs. 0.92 [p = 0.023]), and overall resectability (0.79 vs. 0.92 [p = 0.007]; 0.82 vs. 0.94 [p = 0.021]) in the initial workup group. In the follow-up group, the diagnostic performance of CECT plus PET/MRI was significantly higher than that of CECT imaging for local recurrence (0.81 vs. 1.00 [p = 0.029]; 0.82 vs. 0.94 [p = 0.045]).

Conclusion: PET/MRI may add value to CECT in patients with biliary tract cancer both in the initial workup for staging and determination of overall resectability and in follow-up for local recurrence.

키워드

Positron-emission tomography; Magnetic resonance imaging; Biliary tract neoplasms; Multidetector computed tomography

원문 및 링크아웃 정보

  

등재저널 정보