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당뇨병 치료약제와 심혈관 질환

Anti-Diabetic Drugs in Cardiovascular Disease

대한내과학회지 2021년 96권 2호 p.85 ~ 91
김세은, 유병수,
소속 상세정보
김세은 ( Kim Se-Eun ) - Yonsei University Wonju College of Medicine Department of Internal Division of Cardiology
유병수 ( Yoo Byung-Su ) - Yonsei University Wonju College of Medicine Department of Internal Division of Cardiology

Abstract


Diabetes is one of the important risk factors in cardiovascular disease associated with atherosclerosis, and cardiovascular disease is the leading cause of death in patients with diabetes mellitus. Recent randomized placebo-controlled cardiovascular outcome trials of all new antidiabetic drugs have linked SGLT-2 inhibitors and GLP1-agonists to not only increased cardiovascular stability but significant reduction of cardiovascular disease. These results have led to preferential selection of the most effective and beneficial antidiabetic drugs with the evidence of cardiovascular safety and efficacy. Herein, we address cardiovascular stability and the effectiveness of antidiabetic drugs, focusing on recently developed ones.

키워드

Anti-diabetic drugs; Safety; Cardiovascular outcomes trials

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