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개방각녹내장, 고안압증 환자에서 안구치수의 임상적 의의

The Clinical Significance of Ocular Dimensions in Patients with Open Angle Glaucoma and Ocular Hypertension

건양의대학술지 2005년 5권 1호 p.94 ~ 98
함이룸, 손용호, 김황기, 정윤석,
소속 상세정보
함이룸 ( Hahm I-Rum ) - 건양대학교 의과대학 김안과병원 안과학교실
손용호 ( Sohn Yong-Ho ) - 건양대학교 의과대학 김안과병원 안과학교실
김황기 ( Kim Hwang-Ki ) - 건양대학교 김안과병원 안과학교실
정윤석 ( Chung Yun-Suk ) - 건양대학교 의과대학 김안과병원 안과학교실

Abstract


Purpose: To determine characteristics of ocular dimensions in glaucoma and ocular hypertension and possible correlations between age, tonometry and ocular dimensions.

Methods: Randomly chosen 101 eyes of 101 patients who have not taken any intraocular pressure (IOP)-lowering medications were studied. 21 eyes were diagnosed as primary open angle glaucoma (POAG), 13 eyes as ocular hypertension, 48 eyes as normal tension glaucoma, and 19 eyes were diagnosed as normal. Tonometry, central corneal thickness (CCT), anterior chamber depth, lens thickness, and axial length were measured.

Results: CCT was thinnest in eyes with normal tension glaucoma (534±5 μm), thickest in eyes with ocular hypertension (586±14 μm), and intermediate in eyes with POAG and healthy eyes (539±6 μm and 548±6 μm, respectively). These differences were statistically significant (P=0.0007). Goldmann applanation tonometry and CCT were weakly correlated (r=0.16, P=0.255). Lens thickness was strongly correlated with age (r=0.68, P<0.0001). Anterior chamber depth was negatively correlated with lens thickness and age (r=-0.35, P=0.014 and r=-0.55 P<0.0001). Axial length was correlated with anterior chamber depth and age (r=0.72 P<0.0001 and r=-0.44 P=0.001).

Conclusions: The influence of central corneal thickness on the accuracy of IOP measurement with Goldmann pplanation tonometry appears to be small and not clinically relevant. When corneal thickness is deviated from normal, it would be desirable to take this into account in diagnosis and management of glaucoma.

키워드

Central comeal thickness;Ocular dimension;Tonometry

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