잠시만 기다려 주세요. 로딩중입니다.

괴상형 간세포암 ; 동시 간동맥 항암-방사선요법으로 부분관해 획득 후 근치적 간절제술을 시행한 간세포암 1예

A Case of Curative Resection of Advanced Hepatocellular Carcinoma After Localized Concurrent Chemo-Radiation Therapy

대한간암연구학회지 2009년 9권 1호 p.67 ~ 70
권지숙, 박경식, 이경인, 황재석, 장병국, 정우진, 조광범, 박우영, 이정은, 김은수,
소속 상세정보
권지숙 ( Kwon Jee-Suk ) - 계명대학교 의과대학 내과학교실
박경식 ( Park Kyung-Sik ) - 계명대학교 의과대학 내과학교실
이경인 ( Lee Kyung-In ) - 계명대학교 의과대학 내과학교실
황재석 ( Hwang Jae-Seok ) - 계명대학교 의과대학 내과학교실
장병국 ( Jang Byoung-Kuk ) - 계명대학교 의과대학 내과학교실
정우진 ( Chung Woo-Jin ) - 계명대학교 의과대학 내과학교실
조광범 ( Cho Kwang-Bum ) - 계명대학교 의과대학 내과학교실
박우영 ( Park Woo-Young ) - 계명대학교 의과대학 내과학교실
이정은 ( Lee Jeong-Eun ) - 계명대학교 의과대학 내과학교실
김은수 ( Kim Eun-Soo ) - 계명대학교 의과대학 내과학교실

Abstract


Advanced hepatocellular carcinoma (HCC) with portal vein thrombosis is not suitable candidates for surgical treatment at the most of diagnosis because of poor liver function, extensive tumor involvement of the liver, vascular involvement, and/or intra/extrahepatic metastasis. We attempted localized concurrent chemo-radiation therapy (CCRT) in patients having locally advanced HCC with left and main portal vein thrombosis. We report a case of locally advanced HCC patient who became surgically resectable by downstaging after localized CCRT. Localized CCRT was performed with a total radiation dose of 5,040 cGy (180 cGy×28 times) and hepatic arterial infusion of 5-fluorouracil (5-FU, 250 mg/day) and cisplatin (10 mg/day) for 5 days via implantable port system during the second and the fifth weeks of the radiotherapy. Marked contraction of HCC was noted on follow up computerized tomography (CT) after localized CCRT, and subsequently surgical resection with curative aim was performed. He was gave a additional transcatheter arterial chemoembolization (TACE) because follow up CT revealed intrahepatic metastasis at subcapsular portion of right hepatic lobe after 3 months of operation. The patient is in complete remission status without recurrence to date.

키워드

Hepatocellular carcinoma;Localized concurrent chemo-radiation therapy;Hepatic Lobectomy

원문 및 링크아웃 정보

등재저널 정보