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국내 항생제의 생산 실태와 변화 추세 (Ⅳ)

The Trend of Antibiotic Production in Korea during 1981~2003

감염과화학요법 2005년 37권 5호 p.271 ~ 279
김윤정, 이승환, 강유나, 김원철, 위성헌, 김상일, 김양리, 강문원,
소속 상세정보
김윤정 ( Kim Youn-Jeong ) - 가톨릭대학교 의과대학 내과학교실
이승환 ( Lee Seung-Hwan ) - 가톨릭대학교 의과대학 내과학교실
강유나 ( Kang Yu-Na ) - 가톨릭대학교 의과대학 내과학교실
김원철 ( Kim Won-Chul ) - 가톨릭대학교 의과대학 내과학교실
위성헌 ( Wie Seong-Heon ) - 가톨릭대학교 의과대학 내과학교실
김상일 ( Kim Sang-Il ) - 가톨릭대학교 의과대학 내과학교실
김양리 ( Kim Yang-Ree ) - 가톨릭대학교 의과대학 내과학교실
강문원 ( Kang Moon-Won ) - 가톨릭대학교 의과대학 내과학교실

Abstract


Background: It is difficult to know the actual situation of antibiotic usage in Korea. We investigated the trend of antibiotic production every five years from 1981 to 2003 by using two parameters:the cost and the amount of antibiotics produced in Korea.

Materials & Methods: We analysed the data from "Annual Products of Medicine" published by Korea Pharmaceutical Manufactures Association. All antibiotics were classified into generic names, and the cost and the amount of antibiotic produced were compared with the results from previous years.

Results: The total production cost and the amount of antibiotics increased since 1980 and by 2003, it was 1,306 billion won and 965 tons respectively. However, the increasing rate of production cost has slowed down since 2000. Among all antibiotics produced in Korea, cephalosporins recorded the highest production cost, reaching 595 billion won (45.6%) in 2003. Cephalosporins made the largest portion of the total amount:252 tons (26.2%). Both 3rd and 4th generation cephlosporins have increased gradually. The second most frequently produced antibiotics in terms of amount were penicillins, although it decreased by 25% since 1998. Aminoglycosides showed similar production cost, but the production amount decreased compared to that of 1998. The production amount of quinolones had skyrocketed to 641% from 1998. Tetracyclines, lincosamides, and chloramphenicols insignificantly decreased in both production cost and amount.

Conclusion: There seems to be an increase of antibiotics in production cost and amount in Korea, but the overall increasing rate of the cost has slowed down since 2000. The newer and more expensive antibiotics have grown in production.

키워드

Antibiotic;Production;Cost;Amount

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등재저널 정보

KCI
KoreaMed
KAMS